HAAO, 1-286aa, Human, His tag, E.coli from IBL- America

Supplier Page

Supplier Page from
IBL- America for
HAAO, 1-286aa, Human, His tag, E.coli

Description

HAAO is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. This protein catalyzes the synthesis of quinolinic acid (QUIN) from 3- hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate Nmethyl- D-aspartate receptors